Synthetic Chemistry Services

With about 2 decades of proven track record in providing chemistry services to small, medium and large Biotech and Pharmaceutical companies, Allmpus has a strong team of experienced project leaders engaged in a wide variety of chemistry and consistently upgrading themselves and their teams on latest developments. Our chemistry teams functioning from Mumbai and rest of Maharashtra facilities are provided with the most modern instruments supporting them carry out complex custom synthesis and collaborative medicinal chemistry programs. Our expertise includes providing services in the field of heterocyclics, carbohydrates, peptides, nucleosides, nucleotides, lipids, photo-redox, organo-metallics, PROTACS to name a few. Highly equipped and experienced Analytical team clubbed with a proactive Supply Chain team helps us in delivering a high-quality science with speed and enabling our customers meet their critical timelines.

Synthetic Capabilities

The team has the experience to take on any kind of synthetic challenges involving various types of chemistry including PROTAC, carbohydrate, nucleotide & nucleoside, peptide, heterocyclic, asymmetric, porphyrins, enzymatic chemistry and many others.

• Complex molecules from grams to multi kilos
• Reference compounds and scaffold synthesis
• Small molecules; Analogues for lead generation; Lead optimization
• Focused libraries: 50-200
• Large libraries: >1,000
• Multi-step stereoselective synthesis of chiral molecules
• Expertise in handling photo-chemical reactions
• Chemoenzymatic and resolution techniques for chiral molecules
• Metabolite synthesis
• Flow-chemistry
• Advantages of selecting our chemists to work on your NCEs
• Services with efficient and excellent quality
• Track record of developing complex and multi-step synthetic processes
• Well trained and skilled scientists with diversified experience
• Flexible business models

Custom Synthesis Services

Allmpus specializes in offering flexible and cost-effective solutions to its clients globally to meet their custom organic synthesis requirements. With deep knowledge, experience and infrastructure, our team has extensive analytical and synthetic chemical capabilities in providing a competitive edge to your custom synthesis needs.

1.  Allmpus have land over 45,000 sq. fit in Amravati, Maharashtra, India which was dedicated for the set up and expansion of pharma health care business.

 

2. Currently Allmpus have over 11,000 sq. R&D  laboratory  unit in Amravati, Maharashtra, India. which include three modern R & D laboratory associates with modern fuming hood, Morden equipment’s having capacity to perform all the kinds of organic reaction.

1. Grignard reaction.
2. heterocyclic
3. symmetric
4. microwave
5. enzymatic
6. multi-step synthesis
7. carbohydrate
8. nucleotide & nucleoside
9. Suzuki reaction
10. pyrophoric reaction
11. hydrogenation reaction - Autoclave reactor of 1Lit at R&D level along with 5 Lit and 25 lit scale commercial synthesis
12. Photochemical reaction
13. etc.

3) Morden purification as well as analytical purification technique available at Allmpus

1. Column Chromatography.
2. Combi flash available for purification of day to day products.
3. Preparative HPLC available for critical purification.
4. Preparative DAG HPLC available for large scale purification.

4. At Allmpus rotary evaporator available up to 20 lit capacity is available for scale up batches.

5. Reactor scale from 5-:1.00L in a single site

6. Synthesis of intermediates to support on-going medicinal chemistry programs

7. Final product/intermediates, well-characterized using our analytical laboratory

8. Use of flow chemistry

 

9. Fully equipped of Analytical Laboratory set up is available for R&D support, day to day routine analysis and finished products analysis

1. HNMR – 400MHZ
2.   HPLC Unit - 06 Number
3.   LC_Ms - 01 Number
4.   Preparative HPLC- 01 Number
5.   Preparative DAG HPLC - 01 Number
6.   IR infrared spectroscopy - 01 Number
7.    TGA thermogravimetric - 01 Number
8.   lyophilizer freeze dryer - 01 Number
9.   Melting point apparatus
10.     Ph Meter apparatus
11.     Sonicator
12.   etc.

Impurity profiling / Synthesis of API related Compound, Pharmacopeia impurity

Allmpus laboratories private limited is a research-based pharmaceutical company which can provide flexible solutions to customer's business through science and innovation.

We are the manufacturer and supplier of Impurity Standard as per Pharmacopeia, API related Compound, Process Impurity, Metabolite and are acceptable to all regulatory agencies & also used for ANDA filing /DMF filing and genotoxic study.

We are providing a Right Product/Service to Right Customer at Right Time which helps us to make a long-term relationship with our client. Today Allmpus has made his own place in the market due to extensive product catalogues, Quality, On Time Delivery, Technical support and Best Price.

Specialized and highly dedicated R&D centre for Microloids

At Allmpus doing synthesis, degradation and isolation of pharmacopeial impurities, we have strength on Microloids and most of the impurities we synthesised is unique and we are the only supplier worldwide and supplying to all world.

We have over 5000+ impurities available in stock

Our Products list -https://www.allmpus.com/allmpus-prod-cat

Centre of Excellence: Parallel & Library Synthesis

Parallel synthesis and Library synthesis are two important tools in modern drug discovery. They enable the synthesis of a large number of closely related analogues in a short time following general synthetic transformations. Thus, parallel library synthesis has the potential to reduce the cycle time of medicinal chemistry efforts significantly. Therefore, in the past few decades, we found that the synthesis of focused small molecule libraries are very useful for the optimization of drug leads.

Allmpus has over 15 years of rich experience in the synthesis of custom libraries. We have a strong track record of delivering several focused libraries ranging from 20-300 compounds and large libraries of up to 6000 compounds. We have a dedicated team of highly skilled and experienced chemists capable of performing complex chemical synthesis and purification. We are fully equipped with state-of-the-art infrastructure and highly proficient in parallel synthesis, high throughput purification, compound analysis, and management.

Our capabilities comprise of: